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Faculty Veterinary, Animal and Biomedical Sciences Pharmacology and Toxicology Faculty Members Dr. Md. Rashedunnabi Akanda

Dr. Md. Rashedunnabi Akanda

Professor

DVM, MS, PhD (KR), Postdoc (KR & USA)

Research interests: Phytomedicine | Inflammation | Cancer Biology

akandamr.dph@sau.ac.bd


+8801730721999
Dept. of Pharmacology and Toxicology

Citation indices

  • Total citations: 1445
  • h-index: 18
  • i10-index: 27

Peer Reviewed Selected Articles

  • Akanda MR, Aktaruzzaman M, Tanoy NM, Supty SI, Rahman MA, Riea ATM, Roy S, Sabuj MSS, Ahmed T, Rahman MJ. Bioactive phytochemical-based modulation of inflammatory and oxidative pathways for enhancing tissue regeneration: A narrative review. Regenerative Medicine Reports (): April 07, 2026. DOI: 10.4103/REGENMED.REGENMED-D-25-00029.
  • Sohag TS, Islam S, Islam S, Akanda MR, Siddiqui MSI. Protective role of Silymarin in the mitigation of methotrexate induced biometrical and haemato-biochemical alterations of liver in rabbits. Discover Applied Sciences. 2026, 8:427. doi: 10.1007/s42452-026-08450-2
  • Sabuj MSS, Ahmed T, Rahman MJ, Salam SMA, Park BY, Akanda MR. KMT2A-Mediated transcriptional regulation in stemness and cancer: molecular mechanisms and therapeutic opportunities. Medical Oncology,2025 Dec 24;43(2):62.
  • Sultana T, Islam MS, Salam SMA, Jahan E, Rahman MK, Sabuj MSS, Park BY, Ahmed T. Rahman MJ, Akanda MR. KDM2A demethylase: A versatile epigenetic regulator in development, cancer, and therapeutic horizons. Pathology - Research and Practice 278 (2026) 156336
  • Kim YJ, Sabuj MSS, Akanda MR, Kim IS, DC Ahn, Tae HJ, Park BY. Renoprotective mechanisms of bioconverted wild-simulated ginseng: mitigating oxidative stress, inflammation, and apoptosis to protect against ischemic renal injury via Nrf2/HO-1/NF-κB/Caspase-3 signaling. Journal of Ginseng Research. 2025, October 26.
  • Sohag TS, Islam S, Islam S, Akanda MR, Siddiqui MSI. Protective Role of Silymarin Against Methotrexate Induced Nephropathy in Rabbits. J Biochem Mol Toxicol. 2025 Oct;39(10):e70544.
  • Islam S, Begum S, Islam S, Rahman MM, Khan A, Dev S, Talha MMH, Akanda MR, Hasan MMI. Green tea leaf extract improves physiological, biochemical, and reproductive dynamics in mice. J Adv Biotechnol Exp Ther. 2025 Sep; 8(3): 491-507.
  • Sabuj MSS, Islam MS, Akanda MR, Lee J, Kim R, Lee SH, Kim YJ, Oh JM, Ro HG, Kim IS, Ahn D, Park SY, Tae HJ, Park BY. Macluraparishin C Enhances Neuroprotection Against Oxidative Stress-Induced Neurodegeneration by Activating the Antioxidant/MAPK Signaling Pathway. Mol Neurobiol. 2025 Jun 27.
  • Akanda MR, Sabuj MSS, Salam SMA, Jahan E. Molecular Interplay of Gene Network Dynamics, Epigenetic Regulation, and Therapeutic Mapping in Cardiovascular Disease. Cardiovasc Drugs Ther. 2025.
  • Akanda MR, Kawsar MA, Sabuj MSS, Ashik‑Uz‑Zaman M, Siddiqui MSI, Hossain MA. Microplastic pollution in livestock farming in Bangladesh: a critical review of its key findings and mitigation strategies to address public health. Environ Monit Assess. 2025, 197:732.
  • Akanda MR, Lubaba U, Rahman MK, Islam A, Akter M, Islam MS, Uddin MN, Park BY. Mechanistic role of stromal cancer-associated fibroblasts in tumorigenesis and brain metastasis: Highlighting drug resistance and targeted therapy. Pathology - Research and Practice. 2025, May:269:155918.
  • Islam S, Islam MM, Akhand MRN, Park BY, Akanda MR. Recent advancements in cGAS-STING activation, tumor immune evasion, and therapeutic implications. Medical Oncology. 2024 Oct 18;41(11):291.
  • Rahman A, Chowdhury MSR, Hossain H, Elsaid FG, Almutairi LA, Begum R, Sabrin MS, Akanda MR, Hossain MM, Islam MR, Rahman MM, Rahman MM. Identification of Virulence Genes and Multidrug Resistance in Shiga-Toxin Producing Escherichia coli (STEC) from Migratory and Captive Wild Birds. Pakistan Veterinary Journal. 2024, 44(4): 1120-1130.
  • Ahn EJ, Kim YJ, Akanda MR, Oh SJ, Jung TY, Jung S, Lee JH, Kim SS, Jeong YY, Ha HH, Hyun H, Kim H, Rhee JH, Kim KK, Lee KH, Moon KS. Metastasis-enhancing protein KITENIN confers temozolomide resistance on glioblastoma with unmethylated MGMT via upregulation of cancer stem cell makers. Clinical and Translational Medicine. 2024 Aug;14(8):e1804.
  • Akanda MR, Ahn EJ, Kim YJ, Salam SMA, Noh MG, Lee TK, Kim SS, Lee KH, Moon KS. Analysis of stromal PDGFR-β and α-SMA expression and their clinical relevance in brain metastases of breast cancer patients. BMC Cancer. 2023 May 22;23(1):468.
  • Akanda MR, Ahn EJ, Kim YJ, Salam SMA, Noh MG, Kim SS, Jung TY, Kim IY, Kim CH, Lee KH, Moon KS. Different expression and clinical implications of cancer-associated fibroblast (CAF) markers in brain metastases. Journal of Cancer. 2023 Feb 5;14(3):464-479.
  • Islam MS, Shin HY, Yoo YJ, Lee EY, Kim R, Jang YJ, Akanda MR, Tae HJ, Kim IS, Ahn D, Park BY. Fermented Mentha arvensis administration provides neuroprotection against transient global cerebral ischemia in gerbils and SH-SY5Y cells via downregulation of the MAPK signaling pathway. BMC Complementary Medicine and Therapies. 2022 Jun 25;22(1):172.
  • Talha MMH, Hossain MA, Aktaruzzaman M, Islam MS, Khasnobish A, Akanda MR. Effects of spirulina as a functional ingredient in arsenic-induced broiler diet on growth performance and hematobiochemical parameters. Journal of Advanced Veterinary and Animal Research. 2022 Sep 30;9(3):501-508.
  • Islam MS, Shin HY, Yoo YJ, Kim R, Jang YJ, Akanda MR, Tae HJ, Kim IS, Ahn D, Park BY. Olanzapine Ameliorates Ischemic Stroke-like Pathology in Gerbils and H2O2-Induced Neurotoxicity in SH-SY5Y Cells via Inhibiting the MAPK Signaling Pathway. Antioxidants. 2022 Aug 29;11(9):1697.
  • Akanda MR, Park JS, Noh MG, Ha GH, Park YS, Lee JH, Moon KS, Kim CK, Lee KH. TACC3 Promotes Gastric Carcinogenesis by Promoting Epithelial-mesenchymal Transition Through the ERK/Akt/cyclin D1 Signaling Pathway. Anticancer Research. 2021 Jul;41(7):3349-3361.
  • Cho SH, Shim HJ, Park MR, Choi JN, Akanda MR, Hwang JE, Bae WK, Lee KH, Sun EG, Chung IJ. Lgals3bp suppresses colon inflammation and tumorigenesis through the downregulation of TAK1-NF-κB signaling. Cell Death Discovery. 2021 Apr 6;7(1):65.
  • Hong JH, Noh MG, Akanda MR, Kim YJ, Kim SH, Jung TY, Jung S, Lee JH, Rhee JH, Kim KK, Kim SS, Lee KH, Moon KS. Solitary Fibrous Tumor/Hemangiopericytoma Metastasizes Extracranially, Associated with Altered Expression of WNT5A and MMP9. Cancers. 2021 Mar 7;13(5):1142.
  • JH Cho, A Islam, IS Kim, JH Lee, YJ Yoo, SE Kim, A Jawad, W Tian, HJ Tae, Ahn D, Park BY, Kim K, Lee JH, Lee EY, Shin HY, Akanda MR, Tae HJ, Yoon JC. Pathophysiological and Histopathological Ailments in Asphyxial Cardiac Arrest Induced Ischemic Renal Injury. Pakistan Veterinary Journal. 2021, 41 (1).
  • Islam A, Islam MS, Rahman MK, Uddin MN, Akanda MR. The pharmacological and biological roles of eriodictyol. Archives of Pharmacal Research. 2020 Jun;43(6):582-592.
  • Islam, Islam MS, Uddin MN, Hasan MMI, Akanda MR. The potential health benefits of the isoflavone glycoside genistin. Archives of pharmacal research. 2020 Apr;43(4):395-408.
  • Tian W, Zhao J, Lee JH, Akanda MR, Cho JH, Kim SK, Choi YJ, Park BY. Neuroprotective Effects of Cornus officinalis on Stress-Induced Hippocampal Deficits in Rats and H2O2-Induced Neurotoxicity in SH-SY5Y Neuroblastoma Cells. Antioxidants. 2019 Dec 26;9(1):27.
  • Kim YJ, Kim JH, Kim O, Ahn EJ, Oh SJ, Akanda MR, Oh IJ, Jung S, Kim KK, Lee JH, Kim HS, Kim H, Lee KH, Moon KS. Caveolin-1 enhances brain metastasis of non-small cell lung cancer, potentially in association with the epithelial-mesenchymal transition marker SNAIL. Cancer Cell International. 2019 Jun 28;19:171.
  • Akanda MR, Uddin MN, Kim IS, Ahn D, Tae HJ, Park BY. The biological and pharmacological roles of polyphenol flavonoid tilianin. European journal of pharmacology. 2019 Jan 5;842:291-297.
  • Rao Z, Kim SY, Akanda MR, Lee SJ, Jung ID, Park BY, Kamala-Kannan S, Hur J, Park JH. Enhanced Expression and Functional Characterization of the Recombinant Putative Lysozyme-PMAP36 Fusion Protein. Mol Cells. 2019 Mar 31;42(3):262-269.
  • Kim WK, Moon JY, Cho JS, Ochirkhuyag E, Akanda MR, Park BY, Hur J. Protective efficacy of an inactivated Brucella abortus vaccine candidate lysed by GI24 against brucellosis in Korean black goats. Canadian journal of veterinary research. Canadian Journal of Veterinary Research. 2019 Jan;83(1):68-74.
  • Kim WK, Moon JY, Cho JS, Akanda MR, Park BY, Kug Eo S, Park SY, Lee JH, Hur J. Brucella abortus lysed cells using GI24 induce robust immune response and provide effective protection in Beagles. Pathogens and disease. 2018 Feb 1;76(1).
  • Akanda MR, Nam HH, Tian W, Islam A, Choo BK, Park BY. Regulation of JAK2/STAT3 and NF-κB signal transduction pathways; Veronica polita alleviates dextran sulfate sodium-induced murine colitis. Biomedicine & Pharmacotherapy. 2018 Apr;100:296-303.
  • Akanda MR, Kim MJ, Kim IS, Ahn D, Tae HJ, Rahman MM, Park YG, Seol JW, Nam HH, Choo BK, Park BY. Neuroprotective Effects of Sigesbeckia pubescens Extract on Glutamate-Induced Oxidative Stress in HT22 Cells via Downregulation of MAPK/caspase-3 Pathways. Cellular and Molecular Neurobiology. 2018 Mar;38(2):497-505.
  • Akanda MR, Kim IS, Ahn D, Tae HJ, Nam HH, Choo BK, Kim K, Park BY. Anti-inflammatory and gastroprotective roles of Rabdosia inflexa through downregulation of pro-inflammatory cytokines and MAPK/NF-κB signaling pathways. International journal of molecular sciences. 2018 Feb 16;19(2):584.
  • Tian W, Akanda MR, Islam A, Yang HD, Lee SC, Lee JH, Kim SK, Choi YJ, Im SY, Park BY. The anti-stress effect of Mentha arvensis in immobilized rats. International journal of molecular sciences. 2018 Jan 25;19(2):355.
  • Kim WK, Moon JY, Cho JS, Akanda MR, Park BY, Kug Eo S, Park SY, Lee JH, Hur J. Brucella abortus lysed cells using GI24 induce robust immune response and provide effective protection in Beagles. Pathogens and disease. 2018 Feb 1;76(1).
  • Akanda MR, Kim HY, Park M, Kim IS, Ahn D, Tae HJ, Park BY. Hair growth promoting activity of discarded biocomposite keratin extract. Journal of biomaterials applications. 2017 Aug;32(2):230-241.
  • Liu Y, Liu Y, Park M, Park SJ, Zhang Y, Akanda MR, Park BY, Kim HY. Green synthesis of fluorescent carbon dots from carrot juice for in vitro cellular imaging. Carbon Letters. 21, 61-67.
  • Akanda MR, Kim IS, Ahn D, Tae HJ, Tian W, Nam HH, Choo BK, Park BY. In vivo and in vitro hepatoprotective effects of Geranium koreanum methanolic extract via downregulation of MAPK/Caspase-3 pathway. Evidence-Based Complementary and Alternative Medicine. 2017;2017:8137627.
  • Jamil AB, Akanda MR, Rahman MM, Hossain MA, Islam MS. Prebiotic competence of spirulina on the production performance of broiler chickens. Journal of Advanced Veterinary and Animal Research. 2015, 2(3), 304–309.
  • Hasan MMI, Howlader MMR, Rahman MM, Belal SA, Akanda MR. Effects of garlic supplementation on parasitic infestation, live weight, and hematological parameters in Black Bengal goat. Journal of Advanced Veterinary and Animal Research. 2015, 2 (3).
  • Islam MR, Uddin MN, Akanda MR, Baset MA, Belal SA. Effect of milk urea nitrogen of dairy cows in relation to breed. Iranian Journal of Applied Animal Science. 2015, 5 (2), 279-283.
  • Rahman MM, Kim IS, Ahn DC, Cho HS, Kim Won-Il, Kim B, Kwon J, Akanda MR, Park BY. Expression analysis of ciliary rootlet coiled-coil protein mRNA during Xenopus development. Korean Journal of Veterinary Research. 2015; 55(3):181-184.

Articles (Other)

  • Uddin MN, Toma SA, Hossain MN, Islam O, Khatun S, Begum M, Ahmed SU, Akanda MR. Utilization of spices and herbs in ruminant and non-ruminant diet and its effects on meat quality. International Journal of Natural and Social Sciences. 2021,8 (3), 01-16.
  • Islam MA, Islam MS, Hossain MA, Ahmed S, Aktaruzzaman M, Akanda MR, Talha MMH, Zabir AA. In vitro antibacterial activity of medicinal plants turmeric, chinnamon, and clove against gm (ve) and gm (-ve) bacteria. International Journal of Current Pharmaceutical Research. 2019, 11 (5), 85-88.
  • Uddin F, Hossain MA, Das R, Akanda MR, Islam MS. Evaluation of toxic effects of Datura Leaves (Datura stramonium) in rat. International Journal of Agriculture and Environmental Research. 2017, 3 (4), 3486-3497.
  • Haque MM, Howlader MMR, Akanda MR. Effects of Probiotics on Live Weight and Hematobiochemical Parameters in Broiler. International Journal of Agricultural Science Research. 2015, 2(6), pp. 126-132.
  • Shaha AC, Hossain MA, Islam MS, Akanda MR, Rahman MM, Hasan MMI. Comparative efficacy of neem leaves, pineapple leaves and levamisole against gastrointestinal nematodiasis in sheep. Wayamba Journal of Animal Science. 2015, 7, 1201-1209.
  • Kanon D, Akanda MR, Rahman MM, Islam MS, Hossain MA. Effects of tobacco, neem, and ivermectin against ectoparasites: a comparative study in Black Bengal goats. International Journal of Veterinary Science. 2015, 4 (4), 194-198.
  • Roy AC, Islam MR, MK Hossain, Lucky NS, Akanda MR, Paul B. Effects of various local analgesics and ketamine for cranial epidural analgesia in Black Bengal Goats. International Journal of Biological Research. 2015, (1), 19-24.
  • Hossain MA, Akanda MR, Mostofa M, Awal MA. Therapeutic competence of dried garlic powder (Allium sativum) on biochemical parameters in lead (Pb) exposed broiler chickens. Journal of Advanced Veterinary and Animal Research. 2015, 1 (4), 189-195.
  • Akanda MR, Hasan MMI, Belal SA, Roy AC, Ahmed SU, das R, Masud AA. A survey on prevalence of gastrointestinal parasitic infection in cattle of Sylhet division in Bangladesh. American Journal of Phytomedicine and Clinical Therapeutics. 2015, 2 (7), 855-860.
  • Hossain MA, Akanda MR, Mostofa M, Awal MA. Ameliorative effects of dried garlic powder (Allium sativum) on hematological parameters against lead (Pb) intoxication in broiler chickens. Pharmacologia. 2014, 5 (3), 110-119.
  • Uddin Mn, Ahmed BS, Akanda MR, Uddin MMS, Hasan KMM, Belal SA, Baset MA. Nutritional status of Black Bengal goat in government goat development farm, Sylhet. Annals of Veterinary and Animal Science. 2014, 9, 98.
  • Hossain MA, Akanda MR, Mostofa M, Awal MA. Determination of environmental deposition of lead (Pb) in certain selected samples in the industrial areas of Gazipur District of Bangladesh. International Journal of Research in Agricultural Sciences. 2014, 1 (8), 148-155.
  • Hossain MA, Akanda MR, Hasan MMI, Awal MA. Effects of dried garlic powder (Allium sativum) against the subclinical lead (pb) poisoning in broiler chickens. Wayamba Journal of Animal Science. 2014, 6, 981-991.
  • Kanjilal G, Akanda MR, Hasan MMI, Chowdhury MR, Islam MS, Howlader MMR, Hossain MA. Potency of Protexin®(Mixed Probiotics) on hemato biochemical alteration of commercial broiler. American Journal of Phytomedicine and Clinical Therapeutics. 2014, 2, 650-659.
  • Akanda MR, Islam MS, Hossain MA, Masud AA. Comparative clinical competence of two commercial injectable ivermectin against caprine haemonchosis (Haemonchus contortus). International Journal of Biological Research. 2014, 2 (2), 96-98.
  • Hossain MA, Akanda MR, Belal SA, Hasan MMI, Islam S, Uddin MN, Islam MS, Roy AC. Environmental Deposition of Lead (Pb) in Chickens and Litter Samples Collected from Selected Areas of Bangladesh. Journal of Veterinary Advances. 2014, 4 (9), 677-685.
  • Chowdhury MR, Huq MA, Howlader MMR, Islam MS, Akanda MR, Akhand RN. Comparative efficacies of two different commercial products containing nitroxynil against fascioliasis in cattle. Eurasian Journal of Veterinary Sciences. 2014, 30 (2), 59-62.
  • Akanda MR, Hossain FMA, Uddin MN, Belal SA, Ashad FA, Howlader MMR. Prevalence of gastro-intestinal nematodiasis in Black Bengal goat of Sylhet Govt. Goat Development Farm. Bangladesh. Journal of Research in Biology. 2012, 2 (3), 246-250.
  • Akanda MR, Hosain FMA, Ashad FA, Kabir MG, Howlader MMR. Anthelmintics against gastrointestinal nematodiasis in Black Bengal goat inducing live weight and hematological indices. Pharmacologia. 2012, 3(12), 700-706.

Conference Proceedings

  • American Association for Cancer Research (AACR) Annual Meeting 2020, April 24-29, San Diego Convention Center, San Diego, California, USA.
  • Virtual Meeting, 35th Annual Critical Issues in Tumor Microenvironment: Angiogenesis, Metastasis and Immunology. Edwin L. Steele Lab, October 26-29, 2020, Harvard Medical School, Boston, MA 02115, USA.
  • The 45th Annual Meeting of Korean Cancer Association and the 5th International Cancer Conference, which will be held from June 20 to 21, 2019, in Seoul, Korea.
  • The 59th Annual Meeting of the Korean Neurosurgical Society, October 24th-26th, 2019, Songdo Convensia, Incheon, South Korea.
  • The Annual Meeting of the Korean Societies of Veterinary Science (KSVS), 2015, 2016, and 2017 in South Korea.